• AtHESPERIN: A novel regulator of circadian rhythms with poly(A)-degrading activity in plants 

      Delis C., Krokida A., Tomatsidou A., Tsikou D., Beta R.A.A., Tsioumpekou M., Moustaka J., Stravodimos G., Leonidas D.D., Balatsos N.A.A., Papadopoulou K.K. (2016)
      We report the identification and characterization of a novel gene, AtHesperin (AtHESP) that codes for a deadenylase in Arabidopsis thaliana. The gene is under circadian clock-gene regulation and has similarity to the ...
    • The complex evolutionary history of aminoacyl-tRNA synthetases 

      Chaliotis A., Vlastaridis P., Mossialos D., Ibba M., Becker H.D., Stathopoulos C., Amoutzias G.D. (2017)
      Aminoacyl-tRNA synthetases (AARSs) are a superfamily of enzymes responsible for the faithful translation of the genetic code and have lately become a prominent target for synthetic biologists. Our largescale analysis of > ...
    • Maleness-on-the-Y (MoY) orchestrates male sex determination in major agricultural fruit fly pests 

      Meccariello A., Salvemini M., Primo P., Hall B., Koskinioti P., Dalíková M., Gravina A., Gucciardino M.A., Forlenza F., Gregoriou M.-E., Ippolito D., Monti S.M., Petrella V., Perrotta M.M., Schmeing S., Ruggiero A., Scolari F., Giordano E., Tsoumani K.T., Marec F., Windbichler N., Arunkumar K.P., Bourtzis K., Mathiopoulos K.D., Ragoussis J., Vitagliano L., Tu Z., Papathanos P.A., Robinson M.D., Saccone G. (2019)
      In insects, rapidly evolving primary sex-determining signals are transduced by a conserved regulatory module controlling sexual differentiation. In the agricultural pest Ceratitis capitata (Mediterranean fruit fly, or ...
    • A multifunctional RNA recognition motif in poly(A)-specific ribonuclease with cap and poly(A) binding properties 

      Nilsson, P.; Henriksson, N.; Niedzwiecka, A.; Balatsos, N. A. A.; Kokkoris, K.; Eriksson, J.; Virtanen, A. (2007)
      Poly(A)-specific ribonuclease (PARN) is an oligomeric, processive and cap-interacting 3′ exoribonuclease that efficiently degrades mRNA poly(A) tails. Here we show that the RNA recognition motif (RRM) of PARN harbors both ...
    • The pivotal role of protein phosphorylation in the control of yeast central metabolism 

      Vlastaridis P., Papakyriakou A., Chaliotis A., Stratikos E., Oliver S.G., Amoutzias G.D. (2017)
      Protein phosphorylation is the most frequent eukaryotic post-translational modification and can act as either a molecular switch or rheostat for protein functions. The deliberate manipulation of protein phosphorylation has ...